MAP-kinase-activated kinase 2

Preferred Label : MAP-kinase-activated kinase 2;

MeSH note : a protein kinase which is activated by mitogen-activated protein kinase; phosphorylates tyrosine hydroxylase on serine residues 19 and 40 and activates it; substrate specificity is similar to checkpoint kinase 1 & 2; do not confuse with HSP25, also known as heat-shock protein 25;

CISMeF synonym : HSP25 kinase; MK2 protein, rat;

MeSH synonym : MAP-kinase-activated protein kinase 2; HSP 27 kinase; heat-shock protein 27 kinase; MAPKAP kinase 2; hsp27 kinase; MAPKAP kinase-2; heat shock protein 27 kinase; MAPKAPK2; MAPKAPK-2;

MeSH hyponym : MAPKAP kinase-2, rat; MK2 protein, mouse; mitogen-activated protein kinase-activated protein kinase 2, mouse; MAP kinase-activated protein kinase 2, mouse; MAPKAP kinase 2 protein, mouse; MK2 protein, human; mitogen-activated protein kinase-activated protein kinase 2, human; MAP kinase-activated protein kinase-2, human; MAPKAP kinase-2 protein, human;

MeSH Related Number : Mapkapk2 protein, mouse; MAPKAPK2 protein, human; 2EP8DE2BBS;

Registry Number MeSH : EC 2.7.1.-;

Related CAS MeSH : EC 2.7.1.- (Mapkapk2 protein, mouse); EC 2.7.1.- (MAPKAPK2 protein, human);

Is substance : O;

Details

Origin ID

C084025;

UMLS CUI

C0248446;

MeSH term(s) associated for indexing
- Protein Serine-Threonine Kinases [MeSH Descriptor]
- intracellular signaling peptides and proteins [MeSH Descriptor]
Record concept(s)
- HSP25 kinase [MeSH concept]
- MAP-kinase-activated kinase 2 [MeSH concept]
- MAPKAPK2 protein, human [MeSH concept]
- MK2 protein, rat [MeSH concept]
- Mapkapk2 protein, mouse [MeSH concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]

Keyword's position in hierarchy(ies) :

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