MK 0591 - CISMeF

Preferred Label : MK 0591;

MeSH note : structure given in first source; MK 0591 was previously L-686,708; inhibits leukotriene biosynthesis by inhibiting 5-lipoxygenase activating protein;

CISMeF synonym : 1H-Indole-2-propanoic acid, 1-((4-chlorophenyl)methyl)-3-((1,1-dimethylethyl)thio)-alpha,alpha-dimethyl-5-(2-quinolinylmethoxy)-; 3-(1-(4-chlorobenzyl-3-(t-butylthio)-5-(quinolin-2-ylmethoxy)indol-2-yl))-2,2-dimethyl propanoic acid; L 686708;

MeSH synonym : MK 591; MK-591; MK-0591; MK591 compound;

Related MeSH term : L-686,708;

MeSH Related Number : 321US0I5R6;

Registry Number MeSH : 136668-42-3;

Is substance : O;

Details

Origin ID

C078266;

UMLS CUI

C0210621;

Automatic exact mappings (from CISMeF team)
- Quiflapon [NCIt concept]
MeSH term(s) associated for indexing
- indoles [MeSH Descriptor]
- quinolines [MeSH Descriptor]
Pharmacological action(s)
- 5-Lipoxygenase-Activating protein inhibitors [MeSH Descriptor]
Record concept(s)
- 1H-Indole-2-propanoic acid, 1-((4-chlorophenyl)methyl)-3-((1,1-dimethylethyl)thio)-alpha,alpha-dimethyl-5-(2-quinolinylmethoxy)- [MeSH concept]
- 3-(1-(4-chlorobenzyl-3-(t-butylthio)-5-(quinolin-2-ylmethoxy)indol-2-yl))-2,2-dimethyl propanoic acid [MeSH concept]
- L 686708 [MeSH concept]
- MK 0591 [MeSH concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]

Keyword's position in hierarchy(ies) :

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