cyclo(Trp-Asp-Pro-Val-Leu)

Preferred Label : cyclo(Trp-Asp-Pro-Val-Leu);

MeSH note : derived from the modification of a natural lead of BE-18257B, an endothelin A receptor antagonist; has neuroprotective activity; amino acid sequence given in first source;

CISMeF synonym : BQ 123; cyclo(D-Trp-D-Asp-Pro-D-Val-Leu);

MeSH hyponym : BQ-123; BQ123;

MeSH CAS label : Cyclo(D-alpha-aspartyl-L-prolyl-D-valyl-L-leucyl-D-tryptophyl);

MeSH Related Number : 136553-81-6 (cyclo(D-Trp-D-Asp-Pro-D-Val-Leu));

Registry Number MeSH : 136553-81-6;

Is substance : O;

UNII : S2A8YZM151;

Details

Origin ID

C072247;

UMLS CUI

C0905077;

MeSH indexing information
- receptors, endothelin [MeSH Descriptor]
MeSH term(s) associated for indexing
- peptides, cyclic [MeSH Descriptor]
Pharmacological action(s)
- Endothelin Receptor Antagonists [MeSH Descriptor]
- antihypertensive agents [MeSH Descriptor]
Record concept(s)
- BQ 123 [MeSH concept]
- cyclo(D-Trp-D-Asp-Pro-D-Val-Leu) [MeSH concept]
- cyclo(Trp-Asp-Pro-Val-Leu) [MeSH concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]

Keyword's position in hierarchy(ies) :

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