Preferred Label : proinsulin endopeptidase II;
MeSH note : involved in proteolytic conversion of proinsulin into insulin; cleaves preferentially
on the C-terminal side of Lys 64.Arg 65 of proinsulin (C-peptide/A-chain junction);
pH optinum 5.5; not inhibited by inhibitors of aspartic proteinases;
CISMeF synonym : ca-dependent acidic endoprotease type II; insulin secretory granule type II endopeptidase; calcium dependent acidic endopeptidase II;
Registry Number MeSH : EC 3.4.99.-;
Is substance : O;
Origin ID : C061496;
UMLS CUI : C0072099;
MeSH term(s) associated for indexing
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