proinsulin endopeptidase I

Preferred Label : proinsulin endopeptidase I;

MeSH note : involved in proteolytic conversion of proinsulin into insulin; pH optimum 5.5; cleaves exclusively on the C-terminal side of Arg 31.Arg 32 (B-chain/C-peptide junction); not inhibited by inhibitors of aspartic proteinases;

MeSH synonym : calcium-dependent acidic endopeptidase I; Ca-dependent endopeptidase I;

Registry Number MeSH : EC 3.4.99.-;

Is substance : O;

Details

Origin ID

C054196;

UMLS CUI

C0072098;

MeSH term(s) associated for indexing
- endopeptidases [MeSH Descriptor]
Record concept(s)
- proinsulin endopeptidase I [MeSH concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]

Keyword's position in hierarchy(ies) :

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