U 74500A - CISMeF

Preferred Label : U 74500A;

MeSH note : potent inhibitor of iron-dependent lipid peroxidation; has excellent activity in in vivo models of experimental CNS trauma & ischemia; structure given in first source; RN given is for 3,6-bis(diethylamino) cpd; Cancer Lett 1992;64(1):61-6 uses 5,6-bis(diethylamino) cpd for U 74500A;

CISMeF synonym : 21-(4-(3,6-bis(diethylamino)-2-pyridinyl)-1-piperazinyl)-16-methylpregna-1,4,9(11)triene-3,20-dione HCl; 21-(4-(5,6-bis(diethylamino)-2-pyridinyl)-1-piperazinyl)-16-methylpregna-1,4,9(11)triene-3,20-dione HCl; U 74500E; U74500;

MeSH synonym : U74500A; U-74500A;

Related MeSH term : U74500E; U-74500E;

MeSH CAS label : Pregna-1,4,9(11)-triene-3,20-dione, 21-(4-(3,6-bis(diethylamino)-2-pyridinyl)-1-piperazinyl)-16-methyl-, hydrochloride, (16alpha)-;

MeSH Related Number : 110101-65-0 (U-74500A);

Registry Number MeSH : 110101-65-0;

Is substance : O;

UNII : IDW4RCM01L;

Details

Origin ID

C053356;

UMLS CUI

C0077642;

MeSH term(s) associated for indexing
- pregnatrienes [MeSH Descriptor]
Pharmacological action(s)
- anti-ulcer agents [MeSH Descriptor]
- antioxidants [MeSH Descriptor]
- immunosuppressive agents [MeSH Descriptor]
Record concept(s)
- 21-(4-(3,6-bis(diethylamino)-2-pyridinyl)-1-piperazinyl)-16-methylpregna-1,4,9(11)triene-3,20-dione HCl [MeSH concept]
- 21-(4-(5,6-bis(diethylamino)-2-pyridinyl)-1-piperazinyl)-16-methylpregna-1,4,9(11)triene-3,20-dione HCl [MeSH concept]
- U 74500A [MeSH concept]
- U 74500E [MeSH concept]
- U74500 [MeSH concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]

Keyword's position in hierarchy(ies) :

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