o-succinylbenzoic acid synthase

Preferred Label : o-succinylbenzoic acid synthase;

MeSH note : E coli enzyme; with SHCHC synthase catalyzes formation of o-succinylbenzoic acid from isochorismic acid & alpha-ketoglutarate in presence of thiamine pyropyrophosphate; succinic semialdehyde anion is formed by decarboxylation of alpha-ketoglutarate by thiamine pyrophosphate; anion then attacks isochorismic acid, initiating aromatization with elimination of pyruvate & H2O;

CISMeF synonym : MenC protein, E coli;

MeSH synonym : o-succinylbenzoate synthase; OSB synthase; 2-succinylbenzoic acid synthase; ortho-succinylbenzoic acid synthase;

Registry Number MeSH : EC 4.1.99.-;

Is substance : O;

Details

Origin ID

C052986;

UMLS CUI

C0069280;

MeSH term(s) associated for indexing
- carbon-carbon lyases [MeSH Descriptor]
Record concept(s)
- MenC protein, E coli [MeSH concept]
- o-succinylbenzoic acid synthase [MeSH concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]

Keyword's position in hierarchy(ies) :

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