celastrol - CISMeF

Preferred Label : celastrol;

MeSH note : isolated from Tripterygium wilfordii; structure given in first source; potent inhibitory activity on both Kir2.1 and ERG1 potassium channels, leading to LONG QT SYNDROME;

MeSH synonym : tripterine; 3-hydroxy-24-nor-2-oxo-1(10),3,5,7-friedelatetraen-29-oic acid; tripterin;

MeSH CAS label : 3-hydroxy-24-nor-2-oxo-1(10),3,5,7-friedelatetraen-29-oic acid;

MeSH Related Number : 34157-83-0 (tripterine); 34157-83-0;

Registry Number MeSH : 34157-83-0;

Is substance : O;

UNII : L8GG98663L;

Details

Origin ID

C050414;

UMLS CUI

C0084866;

MeSH indexing information
- tripterygium [MeSH Descriptor]
MeSH term(s) associated for indexing
- pentacyclic triterpenes [MeSH Descriptor]
- triterpenes [MeSH Descriptor]
Record concept(s)
- celastrol [MeSH concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]

Keyword's position in hierarchy(ies) :

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