seglitide - CISMeF

Preferred Label : seglitide;

MeSH note : more potent than somatostatin for inhibition of insulin, glucagon & growth hormone release; used experimentally in treatment of Alzheimer's disease; somatostatin receptor antagonist;

CISMeF synonym : L 363586; MK 678;

MeSH synonym : cyclo(N-methylalanyl-tyrosyl-tryptophyl-lysyl-valyl-phenylalanyl); cyclo(N-Me-Ala-Tyr-Trp-Lys-Val-Phe); cyclo(MATTLVP);

MeSH hyponym : MK-678; seglitide acetate; L-363586;

MeSH CAS label : Cyclic(N-methyl-L-alanyl-L-tyrosyl-D-tryptophyl-L-lysyl-L-valyl-L-phenylalanyl);

MeSH Related Number : seglitide monoacetate; 118232-51-2 (duplicate RN); 81377-02-8 (seglitide); 99248-33-6 (monoacetate); 99248-33-6 (seglitide acetate); URM20C99DG;

Registry Number MeSH : 81377-02-8;

Related CAS MeSH : 99248-33-6 (seglitide monoacetate);

related registry number list (CISMeF) : 118232-51-2 (duplicate RN); 99248-33-6 (monoacetate);

Is substance : O;

UNII : 5P57R7IR6J;

InChIKey : NPJIOCBFOAHEDO-AVWFULIKSA-N;

Details

Origin ID

C040968;

UMLS CUI

C0284783;

Automatic exact mappings (from CISMeF team)
- Seglitide [NCIt concept]
- Seglitide Acetate [NCIt concept]
MeSH indexing information
- somatostatin [MeSH Descriptor]
MeSH term(s) associated for indexing
- peptides, cyclic [MeSH Descriptor]
Pharmacological action(s)
- hormone antagonists [MeSH Descriptor]
Record concept(s)
- L 363586 [MeSH concept]
- MK 678 [MeSH concept]
- seglitide [MeSH concept]
- seglitide monoacetate [MeSH concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Seglitide [NCIt concept]

Keyword's position in hierarchy(ies) :

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