hemoregulatory peptide 5b

Preferred Label : hemoregulatory peptide 5b;

MeSH note : synthetic analog of granulocyte chalone; initially identified in extracts of rodent bone marrow and human leukocytes; monomer inhibits both formation of GM-CFC colonies and cytotoxic drug induced recruitment of murine CRU-S cells into active cell cycle; dimer has stimulatory activity;

MeSH synonym : SP1 pentapeptide; Glp-Glu-Asp-Cys-Lys-OH; pyroglutamyl-glutamyl-aspartyl-cysteinyl-lysine; pGlu-Glu-Asp-Cys-Lys-OH; hp 5B; pEEDCK;

MeSH CAS label : L-Lysine, N2-(N-(N-(N-(5-oxo-L-prolyl)-L-alpha-glutamyl)-L-alpha-aspartyl)-L-cysteinyl)-;

Registry Number MeSH : 84588-89-6;

Is substance : O;

Details

Origin ID

C040758;

UMLS CUI

C0062486;

MeSH indexing information
- colony-stimulating factors [MeSH Descriptor]
- hematopoiesis [MeSH Descriptor]
MeSH term(s) associated for indexing
- oligopeptides [MeSH Descriptor]
- pyrrolidonecarboxylic acid [MeSH Descriptor]
Pharmacological action(s)
- growth inhibitors [MeSH Descriptor]
Record concept(s)
- hemoregulatory peptide 5b [MeSH concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]

Keyword's position in hierarchy(ies) :

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