pegloticase - CISMeF

Preferred Label : pegloticase;

MeSH note : uricase covalently attached to polyethylene glycol, modifying 71% of amino groups & retaining 11% of activity without eliciting antibody response in mice or man; used for lowering serum uric acid;

CISMeF synonym : krystexxa; mountain view pharmaceuticals brand of pegloticase; puricase; savient pharmaceuticals brand of pegloticase;

MeSH synonym : PEG-uricase; polyethylene glycol-uricase; methoxypolyethylene glycol uricase;

Is substance : O;

UNII : R581OT55EA;

Details

Origin ID

C031545;

UMLS CUI

C2350656;

ATC code(s)
- pegloticase [ATC Code]
ATC code(s)
- pegloticase [ATC Code]
Automatic exact mappings (from CISMeF team)
- Pegloticase [NCIt concept]
- Pegloticase (substance) [SNOMED CT concept]
MeSH indexing information
- enzymes, immobilized [MeSH Descriptor]
MeSH term(s) associated for indexing
- polyethylene glycols [MeSH Descriptor]
- urate oxidase [MeSH Descriptor]
Record concept(s)
- krystexxa [MeSH concept]
- pegloticase [MeSH concept]
- puricase [MeSH concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Pegloticase [NCIt concept]
- Pegloticase (substance) [SNOMED CT concept]
- Product containing pegloticase (medicinal product) [SNOMED CT concept]
- pegloticase [ATC Code]
Validated automatic mappings to BTNT
- pegloticase [ATC Code]

Keyword's position in hierarchy(ies) :

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