lofexidine - CISMeF

Preferred Label : lofexidine;

MeSH note : reduces narcotic withdrawal symptoms; RN given refers to parent cpd without isomeric designation; structure in Negwer, 5th ed, #6247;

CISMeF synonym : BritLofex; britannia brand of lofexidine monohydrochloride;

MeSH synonym : 2-(alpha-(2,6-dichlorophenoxy)ethyl) delta-2-imidazoline;

MeSH hyponym : lofexidine monohydrochloride; Lofexidine mono-hydrochloride;

MeSH CAS label : 1H-imidazole, 2-(1-(2,6-dichlorophenoxy)ethyl)-4,5-dihydro-;

MeSH Related Number : lofexidine, ( -)-isomer; lofexidine hydrochloride; 21498-08-8 (lofexidine hydrochloride); 31036-80-3 (lofexidine); 73372-53-9; V47G1SDI1B;

Registry Number MeSH : 31036-80-3;

Related CAS MeSH : 73372-53-9 (lofexidine, ( -)-isomer); V47G1SDI1B (lofexidine hydrochloride);

related registry number list (CISMeF) : 21498-08-8 (mono-HCl); 73372-53-9 (( -)-isomer);

Is substance : O;

UNII : UI82K0T627;

InChIKey : KSMAGQUYOIHWFS-UHFFFAOYSA-N;

Details

Origin ID

C025655;

UMLS CUI

C0065152;

ATC code(s)
- lofexidine [ATC Code]
ATC code(s)
- lofexidine [ATC Code]
MeSH term(s) associated for indexing
- clonidine [MeSH Descriptor]
Pharmacological action(s)
- adrenergic alpha-2 receptor agonists [MeSH Descriptor]
- antihypertensive agents [MeSH Descriptor]
- narcotic antagonists [MeSH Descriptor]
Record concept(s)
- BritLofex [MeSH concept]
- Lucemyra [MeSH concept]
- lofexidine [MeSH concept]
- lofexidine hydrochloride [MeSH concept]
- lofexidine, (+-)-isomer [MeSH concept]
See also inter- (CISMeF)
- Product containing lofexidine (medicinal product) [SNOMED CT concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Lofexidine [NCIt concept]
- Lofexidine (substance) [SNOMED CT concept]
- Product containing lofexidine (medicinal product) [SNOMED CT concept]
- lofexidine [ATC Code]
Validated automatic mappings to BTNT
- Lofexidine Hydrochloride [NCIt concept]
- Lofexidine hydrochloride (substance) [SNOMED CT concept]
- lofexidine [ATC Code]

Keyword's position in hierarchy(ies) :

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