alpha-sarcin - CISMeF

Preferred Label : alpha-sarcin;

MeSH note : basic protein 150 aa, MW 16 kDa; isolated from aspergillus giganteus; sequence similarity with ribonucleases such as RIBONUCLEASE T1; 85% identity with restrictocin; a ribotoxin cleaving the phosphodiester bond on the 3' side of G4325 in the alpha-sarcin/ricin domain of rat 28S RIBOSOMAL RNA; sometimes called a ribosome-inactivating protein but falls outside the normal definition of plant RIP that de-adenylate rRNA;

MeSH CAS label : 1407-48-3;

Registry Number MeSH : 1407-48-3;

Is substance : O;

Details

Origin ID

C014801;

UMLS CUI

C0051464;

Automatic exact mappings (from CISMeF team)
- rRNA endonuclease activity [GO term]
MeSH term(s) associated for indexing
- endoribonucleases [MeSH Descriptor]
- fungal proteins [MeSH Descriptor]
Pharmacological action(s)
- protein synthesis inhibitors [MeSH Descriptor]
Record concept(s)
- alpha-sarcin [MeSH concept]
See also inter- (CISMeF)
- Ribosomal ribonucleic acid endonuclease (substance) [SNOMED CT concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- Ribosomal ribonucleic acid endonuclease (substance) [SNOMED CT concept]

Keyword's position in hierarchy(ies) :

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