Preferred Label : sitaxsentan;

MeSH note : endothelin A receptor antagonist; structure in first source;

CISMeF synonym : TBC-11251;

MeSH synonym : N-(4-chloro-3-methyl-5-isoxazolyl)-2-(3,4-(methylenedioxy)-6-methyl)phenylacetyl-3-thiophenesulfonamide; N-(4-chloro-3-methyl-5-isoxazolyl)-2-((4,5-(methylenedioxy)-O-toly)acetyl)-3-thiophenesulfonamide;

MeSH hyponym : TBC 11251; TBC11251;

Is substance : O;

UNII : J9QH779MEM;

Details


Main resources

You can consult :


https://www.ema.europa.eu/medicines/human/EPAR/Thelin
2011
false
United Kingdom
French
English
syndication feed
syndication feed
Endothelin A Receptor Antagonists
Endothelin A Receptor Antagonists
Endothelin A Receptor Antagonists
Endothelin A Receptor Antagonists
hypertension, pulmonary
hypertension, pulmonary
adult
adult
drug interactions
drug interactions
treatment outcome
treatment outcome
drug evaluation
drug evaluation
isoxazoles
isoxazoles
thiophenes
thiophenes
sitaxentan
sitaxentan
sitaxsentan
sitaxsentan
orphan drug production
orphan drug production
sitaxsentan
sitaxsentan
isoxazoles
isoxazoles
thiophenes
thiophenes
drug evaluation
drug evaluation
summary of product characteristics
summary of product characteristics
package leaflet
package leaflet

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https://www.healthycanadians.gc.ca/recall-alert-rappel-avis/hc-sc/2010/16113a-fra.php
https://www.healthycanadians.gc.ca/recall-alert-rappel-avis/hc-sc/2010/14627a-fra.php
2010
Canada
French
English
sitaxsentan
orphan drug production
Safety-Based drug withdrawals
hypertension, pulmonary
administration, oral
sitaxentan
thiophenes
isoxazoles
receptors, endothelin
liver diseases
isoxazoles
thiophenes
pharmacovigilance note
patient education handout

---
https://www.cadth.ca/sites/default/files/cdr/complete/cdr_complete_Thelin_January-30-2008_fr.pdf
2008
Canada
French
canada
insurance, health, reimbursement
hypertension, pulmonary
isoxazoles
thiophenes
receptors, endothelin
sitaxsentan
sitaxentan
isoxazoles
thiophenes
drug evaluation

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http://www.has-sante.fr/display.jsp?id=c_560668
http://www.has-sante.fr/upload/docs/application/pdf/ct-4468_thelin_.pdf
http://www.has-sante.fr/upload/docs/application/pdf/2010-04/thelin_ct_4468.pdf
2007
France
French
administration, oral
administration, oral
orphan drug production
orphan drug production
sitaxsentan
sitaxsentan
isoxazoles
isoxazoles
thiophenes
thiophenes
sitaxentan
sitaxentan
hypertension, pulmonary
hypertension, pulmonary
treatment outcome
treatment outcome
tablets
tablets
isoxazoles
isoxazoles
thiophenes
thiophenes
evaluation of the transparency committee
evaluation of the transparency committee

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06/09/2025


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