Cytochrome P-450 CYP2C8

Preferred Label : Cytochrome P-450 CYP2C8;

Obsolete resource : false;

MeSH definition : A liver microsomal cytochrome P450 hydroxylase that oxidizes a broad spectrum of substrates including STEROIDS, FATTY ACIDS, and XENOBIOTICS. Examples of pharmaceutical substrates for CYP2C8 include; PACLITAXOL; torsemide; and; AMODIAQUINE;

MeSH synonym : CYP2C8, Cytochrome P-450; Cytochrome P 450 CYP2C8; P-450 CYP2C8, Cytochrome; S-Mephenytoin 4-Hydroxylase; 4-Hydroxylase, S-Mephenytoin; S Mephenytoin 4 Hydroxylase; Cytochrome P450 MP-20; Cytochrome P450 MP 20; P450 MP-20, Cytochrome; Cytochrome P450, Family 2, Subfamily C, Polypeptide 8; CYP2C8; CYPIIC8;

Registry Number MeSH : EC 1.14.14.1;

UNII : EC 1.14.14.1;

Details

Origin ID

D065727;

UMLS CUI

C1382144;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Currated CISMeF NLP mapping
- Cytochrome p450 CYP2C8 enzyme (substance) [SNOMED CT concept]
Record concept(s)
- Cytochrome P-450 CYP2C8 [MeSH concept]
Related MeSH Supplementary Concept(s)
- CYP2C8 protein, human [MeSH Supplementary Concept]
- CYP2C8 protein, mouse [MeSH Supplementary Concept]
Related MeSH term(s)
- Cytochrome P-450 CYP2C8 Inhibitors [MeSH Descriptor]
See also (suggested by CISMeF)
- Cytochrome P-450 CYP2C8 Inducers [MeSH Descriptor]
- Cytochrome P-450 CYP2C8 Inhibitors [MeSH Descriptor]
See also inter- (CISMeF)
- CYP2C8 Inducer [NCIt concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- Cytochrome p450 CYP2C8 enzyme (substance) [SNOMED CT concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients