Hyperpolarization-Activated cyclic Nucleotide-Gated channels

Preferred Label : Hyperpolarization-Activated cyclic Nucleotide-Gated channels;

MeSH definition : A subgroup of cyclic nucleotide-regulated ION CHANNELS of the superfamily of pore-loop cation channels that are opened by hyperpolarization rather than depolarization. The ion conducting pore passes SODIUM, CALCIUM, and POTASSIUM cations with a preference for potassium.;

MeSH synonym : hyperpolarization activated cyclic nucleotide gated channels; hyperpolarization Cyclic-Nucleotide gated ion channels; hyperpolarization cyclic nucleotide gated ion channels; ih cation channels; cation channels, ih; channels, ih cation; I(h) cation channels; I(h) channels; HCN pacemaker channels; channels, HCN pacemaker; pacemaker channels, HCN; Hyperpolarization-Activated cation channel; cation channel, Hyperpolarization-Activated; channel, Hyperpolarization-Activated cation; hyperpolarization activated cation channel;

MeSH hyponym : HCN1 channel; HCN2 channel; HCN3 channel; HCN4 channel; Channel, HCN4; Hyperpolarization Cyclic-Nucleotide Gated Cation Channel 4; Hyperpolarization Cyclic Nucleotide Gated Cation Channel 4; Channel, HCN3; Hyperpolarization Cyclic-Nucleotide Gated Cation Channel 3; Hyperpolarization Cyclic Nucleotide Gated Cation Channel 3; Channel, HCN1; Hyperpolarization Cyclic-Nucleotide Gated Cation Channel 1; Hyperpolarization Cyclic Nucleotide Gated Cation Channel 1; Channel, HCN2; Potassium-Sodium Hyperpolarization-Activated Cyclic Nucleotide-Gated Channel 2; Potassium Sodium Hyperpolarization Activated Cyclic Nucleotide Gated Channel 2; HCN2 Potassium Channel; Channel, HCN2 Potassium; Potassium Channel, HCN2; Hyperpolarization Activated Cyclic Nucleotide-Gated Potassium Channel 2; Hyperpolarization Activated Cyclic Nucleotide Gated Potassium Channel 2;

Is substance : O;

Details

Origin ID

D064428;

UMLS CUI

C1956068;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- hyperpolarization activated cyclic nucleotide gated potassium and sodium channel 2 [HGNC gene]
Record concept(s)
- HCN1 channel [MeSH concept]
- HCN2 channel [MeSH concept]
- HCN3 channel [MeSH concept]
- HCN4 channel [MeSH concept]
- Hyperpolarization-Activated cyclic Nucleotide-Gated channels [MeSH concept]
Related MeSH Supplementary Concept(s)
- HCN1 protein, human [MeSH Supplementary Concept]
- HCN2 protein, human [MeSH Supplementary Concept]
- HCN3 protein, human [MeSH Supplementary Concept]
- HCN3 protein, mouse [MeSH Supplementary Concept]
- HCN3 protein, rat [MeSH Supplementary Concept]
- HCN4 protein, human [MeSH Supplementary Concept]
- HCN4 protein, rat [MeSH Supplementary Concept]
- Hcn1 protein, mouse [MeSH Supplementary Concept]
- Hcn1 protein, rat [MeSH Supplementary Concept]
- Hcn2 protein, mouse [MeSH Supplementary Concept]
- Hcn2 protein, rat [MeSH Supplementary Concept]
- Hcn4 protein, mouse [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]

Keyword's position in hierarchy(ies) :

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