telomere shortening

Preferred Label : telomere shortening;

MeSH definition : The loss of some TELOMERE sequence during DNA REPLICATION of the first several base pairs of a linear DNA molecule; or from DNA DAMAGE. Cells have various mechanisms to restore length (TELOMERE HOMEOSTASIS.) Telomere shortening is involved in the progression of CELL AGING.;

MeSH synonym : shortening, telomere; shortenings, telomere; telomere shortenings;

Details

Origin ID

D059506;

UMLS CUI

C1515263;

Allowable qualifiers
- drug effects [MeSH Qualifier]
- genetics [MeSH Qualifier]
- immunology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
CISMeF manual mappings
- Short telomere length [HPO term]
Currated CISMeF NLP mapping
- Telomere Shortening [NCIt concept]
Record concept(s)
- telomere shortening [MeSH concept]
See also
- telomere homeostasis [MeSH Descriptor]
Semantic type(s)
- Cell or Molecular Dysfunction [UMLS semantic type]
UMLS correspondences (same concept)
- Telomere Shortening [NCIt concept]

Keyword's position in hierarchy(ies) :

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