receptors, purinergic P2X4

Preferred Label : receptors, purinergic P2X4;

MeSH definition : A widely distributed purinergic P2X receptor subtype that plays a role in pain sensation. P2X4 receptors found on MICROGLIA cells may also play a role in the mediation of allodynia-related NEUROPATHIC PAIN.;

MeSH synonym : P2X4 receptors, purinergic; purinergic P2X4 receptors; P2X4 receptor; receptor, P2X4; purinergic receptor P2X, Ligand-Gated ion channel, 4; P2X4 purinoceptor; purinoceptor, P2X4;

Is substance : O;

Details

Origin ID

D058848;

UMLS CUI

C0384613;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- analysis [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- physiology [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- Purinergic receptor p2x, ligand-gated ion channel, 4 [OMIM gene]
Record concept(s)
- receptors, purinergic P2X4 [MeSH concept]
Related MeSH Supplementary Concept(s)
- P2RX4 protein, human [MeSH Supplementary Concept]
- P2rx4 protein, mouse [MeSH Supplementary Concept]
- P2rx4 protein, rat [MeSH Supplementary Concept]
Related MeSH term(s)
- purinergic P2X receptor agonists [MeSH Descriptor]
- purinergic P2X receptor antagonists [MeSH Descriptor]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Receptor [UMLS semantic type]

Keyword's position in hierarchy(ies) :

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