class ia phosphatidylinositol 3-Kinase

Preferred Label : class ia phosphatidylinositol 3-Kinase;

MeSH definition : A phosphatidylinositol 3-kinase subclass that includes enzymes formed through the heterodimerization of a p110 catalytic and a p85, p55, or p50 regulatory subunit. This subclass of enzymes is a downstream target of TYROSINE KINASE RECEPTORS and G PROTEIN-COUPLED RECEPTORS.;

MeSH synonym : phosphatidylinositol 3-Kinase, class ia; phosphatidylinositol 3 kinase, class ia; class ia phosphatidylinositol 3-Kinases; class ia phosphatidylinositol 3 kinases; class ia phosphatidylinositol 3 kinase;

MeSH hyponym : class ia phosphatidylinositol 3-Kinase, p55alpha subunit; class ia phosphatidylinositol 3-Kinase, p55gamma subunit; class ia phosphatidylinositol 3-Kinase, p110delta subunit; class ia phosphatidylinositol 3-Kinase, p85beta subunit; class ia phosphatidylinositol 3-Kinase, p85alpha subunit; class ia phosphatidylinositol 3-Kinase, p110alpha subunit; class ia phosphatidylinositol 3-Kinase, p50alpha subunit; class ia phosphatidylinositol 3-Kinase, p110beta subunit; Class Ia Phosphatidylinositol 3 Kinase, p110beta Subunit; Phosphoinositide-3-Kinase, Catalytic, beta Polypeptide; p110beta Subunit, Class Ia Phosphatidylinositol 3-Kinase; p110beta Subunit, Class Ia Phosphatidylinositol 3 Kinase; Class Ia Phosphatidylinositol 3 Kinase, p110delta Subunit; Phosphoinositide-3-Kinase, Catalytic, delta Polypeptide; p110delta Subunit, Class Ia Phosphatidylinositol 3-Kinase; p110delta Subunit, Class Ia Phosphatidylinositol 3 Kinase; Class Ia Phosphatidylinositol 3 Kinase, p85beta Subunit; p85beta Subunit, Class Ia Phosphatidylinositol 3-Kinase; p85beta Subunit, Class Ia Phosphatidylinositol 3 Kinase; Phosphoinositide-3-Kinase, Regulatory Subunit 2; Phosphoinositide 3 Kinase, Regulatory Subunit 2; Class Ia Phosphatidylinositol 3-kinase, Regulatory, beta Polypeptide; Class Ia Phosphatidylinositol 3 Kinase, p55alpha Subunit; p55alpha Subunit, Class Ia Phosphatidylinositol 3-Kinase; p55alpha Subunit, Class Ia Phosphatidylinositol 3 Kinase; Class Ia Phosphatidylinositol 3 Kinase, p55gamma Subunit; p55gamma Subunit, Class Ia Phosphatidylinositol 3-Kinase; p55gamma Subunit, Class Ia Phosphatidylinositol 3 Kinase; Phosphoinositide-3-Kinase, Regulatory Subunit 3; Phosphoinositide 3 Kinase, Regulatory Subunit 3; Class Ia Phosphatidylinositol 3-kinase, Regulatory, gamma Polypeptide; Class Ia Phosphatidylinositol 3 Kinase, p85alpha Subunit; Phosphoinositide-3-Kinase, Regulatory Subunit 1; Phosphoinositide 3 Kinase, Regulatory Subunit 1; p85alpha Subunit, Class Ia Phosphatidylinositol 3-Kinase; p85alpha Subunit, Class Ia Phosphatidylinositol 3 Kinase; alpha-P85 Subunit, PI-3K; PI-3K alpha-P85 Subunit; Class Ia Phosphatidylinositol 3-kinase, Regulatory, alpha Polypeptide; Class Ia Phosphatidylinositol 3 Kinase, p110alpha Subunit; Phosphoinositide-3-Kinase, Catalytic, alpha Polypeptide; p110alpha Subunit, Class Ia Phosphatidylinositol 3-Kinase; p110alpha Subunit, Class Ia Phosphatidylinositol 3 Kinase; Class Ia Phosphatidylinositol 3 Kinase, p50alpha Subunit; p50alpha Subunit, Class Ia Phosphatidylinositol 3-Kinase; p50alpha Subunit, Class Ia Phosphatidylinositol 3 Kinase;

MeSH Related Number : class ia phosphatidylinositol 3-Kinase, p110alpha subunit; class ia phosphatidylinositol 3-Kinase, p50alpha subunit; class ia phosphatidylinositol 3-Kinase, p110beta subunit; class ia phosphatidylinositol 3-Kinase, p110delta subunit; class ia phosphatidylinositol 3-Kinase, p55alpha subunit; EC 2.7.1.137; EC 2.7.1.154;

Registry Number MeSH : EC 2.7.1.137;

Related CAS MeSH : EC 2.7.1.154 (Class ia phosphatidylinositol 3-Kinase, p110beta subunit); EC 2.7.1.154 (Class ia phosphatidylinositol 3-Kinase, p110delta subunit); EC 2.7.1.137 (Class ia phosphatidylinositol 3-Kinase, p55alpha subunit); EC 2.7.1.154 (Class ia phosphatidylinositol 3-Kinase, p110alpha subunit); EC 2.7.1.137 (Class ia phosphatidylinositol 3-Kinase, p50alpha subunit);

Is substance : O;

UNII : EC 2.7.1.137;

Details

Origin ID

D058543;

UMLS CUI

C2936429;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Indexing information
- 2-(1-(7-methyl-2-morpholin-4-yl-4-oxo-4H-pyrido(1,2-a)pyrimidin-9-yl)ethylamino)benzoic acid [MeSH Supplementary Concept]
- 2-(2-(2-methyl-2,3-dihydroindol-1-yl)-2-oxoethyl)-6-morpholin-4-yl-3H-pyrimidin-4-one [MeSH Supplementary Concept]
- N'-((6-bromoimidazo(1,2-a)pyridin-3-yl)methylene)-N-ethyl-2-methyl-5-nitrobenzohydrazide [MeSH Supplementary Concept]
- idelalisib [MeSH Supplementary Concept]
Record concept(s)
- class ia phosphatidylinositol 3-Kinase [MeSH concept]
- class ia phosphatidylinositol 3-Kinase, p110alpha subunit [MeSH concept]
- class ia phosphatidylinositol 3-Kinase, p110beta subunit [MeSH concept]
- class ia phosphatidylinositol 3-Kinase, p110delta subunit [MeSH concept]
- class ia phosphatidylinositol 3-Kinase, p50alpha subunit [MeSH concept]
- class ia phosphatidylinositol 3-Kinase, p55alpha subunit [MeSH concept]
- class ia phosphatidylinositol 3-Kinase, p55gamma subunit [MeSH concept]
- class ia phosphatidylinositol 3-Kinase, p85alpha subunit [MeSH concept]
- class ia phosphatidylinositol 3-Kinase, p85beta subunit [MeSH concept]
Related MeSH Supplementary Concept(s)
- PI3KR1 protein, human [MeSH Supplementary Concept]
- PIK3R1 protein, human [MeSH Supplementary Concept]
- PIK3R2 protein, rat [MeSH Supplementary Concept]
- Pik3r1 protein, mouse [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]

Keyword's position in hierarchy(ies) :

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