class I phosphatidylinositol 3-Kinases

Preferred Label : class I phosphatidylinositol 3-Kinases;

MeSH definition : A phosphatidylinositol 3-kinase subclass that includes enzymes with a specificity for 1-phosphatidylinositol, 1-phosphatidylinositol 4-phosphate, and 1-phosphatidylinositol 4,5-bisphosphate. Members of this enzyme subclass are activated by cell surface receptors and occur as heterodimers of enzymatic and regulatory subunits.;

MeSH synonym : class I phosphatidylinositol 3-Kinase; class I phosphatidylinositol 3 kinase; phosphatidylinositol 3-Kinase, class I; phosphatidylinositol 3 kinase, class I; class I phosphatidylinositol 3 kinases;

MeSH Related Number : EC 2.7.1.154;

Registry Number MeSH : EC 2.7.1.137;

Is substance : O;

UNII : EC 2.7.1.137;

Details

Origin ID

D058534;

UMLS CUI

C2936422;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Indexing information
- 4-(2-((6-methoxypyridin-3-yl)amino)-5-((4-(methylsulfonyl)piperazin-1-yl)methyl)pyridin-3-yl)-6-methyl-1,3,5-triazin-2-amine [MeSH Supplementary Concept]
- Alpelisib [MeSH Supplementary Concept]
- CH 5132799 [MeSH Supplementary Concept]
Record concept(s)
- class I phosphatidylinositol 3-Kinases [MeSH concept]
Related MeSH Supplementary Concept(s)
- 1-phosphatidylinositol 3-kinase p110 subunit, mouse [MeSH Supplementary Concept]
- Activated PI3K-delta Syndrome [MeSH Supplementary Concept]
- PIK3CA protein, human [MeSH Supplementary Concept]
- PIK3CB protein, human [MeSH Supplementary Concept]
- PIK3CD protein, human [MeSH Supplementary Concept]
- Pik3ca protein, mouse [MeSH Supplementary Concept]
- Pik3cb protein, mouse [MeSH Supplementary Concept]
- Pik3cd protein, mouse [MeSH Supplementary Concept]
- p110delta protein, rat [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]

Keyword's position in hierarchy(ies) :

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