Preferred Label : cyclic nucleotide phosphodiesterases, type 1;
MeSH definition : A CALCIUM and CALMODULIN-dependent cyclic nucleotide phosphodiesterase subfamily.
The three members of this family are referred to as type 1A, type 1B, and type 1C
and are each product of a distinct gene. In addition, multiple enzyme variants of
each subtype can be produced due to multiple alternative mRNA splicing. Although the
type 1 enzymes are classified as 3',5'-cyclic-AMP phosphodiesterases (EC 3.1.4.17),
some members of this class have additional specificity for CYCLIC GMP.;
MeSH synonym : ca-cam-phosphodiesterase; calcium-calmodulin-dependent phosphodiesterase; calcium-calmodulin-stimulated cyclic amp phosphodiesterase; calmodulin dependent cgmp phosphodiesterase; calmodulin dependent phosphodiesterase; calmodulin phosphodiesterase; cgmp phosphodiesterase, calmodulin-dependent; cyclic nucleotide phosphodiesterases, type i; phosphodiesterase, calcium-calmodulin-dependent; ca calmodulin dependent cyclic amp phosphodiesterase; ca cam phosphodiesterase; calcium calmodulin dependent phosphodiesterase; pde1 phosphodiesterases; phosphodiesterases, pde1; calmodulin-dependent cgmp phosphodiesterase; phosphodiesterase, calmodulin-dependent cgmp; calmodulin-dependent phosphodiesterase; cyclic nucleotide phosphodiesterase pde1 family; ca(2 )-cam-stimulated pde; calcium calmodulin stimulated cyclic amp phosphodiesterase;
MeSH hyponym : cyclic nucleotide phosphodiesterases, type 1C; cyclic nucleotide phosphodiesterases, type 1A; cyclic nucleotide phosphodiesterases, type 1B; Phosphodiesterase 1B, Calmodulin-Dependent; Calmodulin-Dependent Phosphodiesterase 1B; Phosphodiesterase 1B, Calmodulin Dependent; Phosphodiesterase 1C, Calmodulin-Dependent; Calmodulin-Dependent Phosphodiesterase 1C; Phosphodiesterase 1C, Calmodulin Dependent; Phosphodiesterase 1A, Calmodulin-Dependent; Calmodulin-Dependent Phosphodiesterase 1A; Phosphodiesterase 1A, Calmodulin Dependent;
CISMeF hyponym : EC 3.1.4.17;
MeSH Related Number : cyclic nucleotide phosphodiesterases, type 1B; cyclic nucleotide phosphodiesterases, type 1A; cyclic nucleotide phosphodiesterases, type 1C; EC 3.1.4.17; EC 3.1.4.35;
Registry Number MeSH : EC 3.1.4.17;
Related CAS MeSH : EC 3.1.4.17 (Cyclic nucleotide phosphodiesterases, type 1B); EC 3.1.4.17 (Cyclic nucleotide phosphodiesterases, type 1C); EC 3.1.4.17 (Cyclic nucleotide phosphodiesterases, type 1A);
Is substance : O;
UNII : EC 3.1.4.17;
Origin ID : D054677;
UMLS CUI : C0081888;
Allowable qualifiers
- Automatic exact mappings (from CISMeF team)
- Record concept(s)
- Related MeSH Supplementary Concept(s)
- Semantic type(s)
A CALCIUM and CALMODULIN-dependent cyclic nucleotide phosphodiesterase subfamily.
The three members of this family are referred to as type 1A, type 1B, and type 1C
and are each product of a distinct gene. In addition, multiple enzyme variants of
each subtype can be produced due to multiple alternative mRNA splicing. Although the
type 1 enzymes are classified as 3',5'-cyclic-AMP phosphodiesterases (EC 3.1.4.17),
some members of this class have additional specificity for CYCLIC GMP.
