dual specificity phosphatase 1

Preferred Label : dual specificity phosphatase 1;

MeSH definition : A dual specificity phosphatase subtype that plays a role in intracellular signal transduction by inactivating MITOGEN-ACTIVATED PROTEIN KINASES. It has specificity for P38 MITOGEN-ACTIVATED PROTEIN KINASES and JNK MITOGEN-ACTIVATED PROTEIN KINASES.;

MeSH synonym : cl100 phosphatase; map kinase phosphatase 1; mitogen activated protein phosphatase 1; phosphatase, mapk; phosphatase, mkp-1; phosphatase, 3ch134; phosphatase-1, map; phosphatase-1, mitogen-activated protein; protein phosphatase-1, mitogen-activated; 3ch134 phosphatase; phosphatase, cl100; externally regulated phosphatase (erp); mapk phosphatase; mitogen-activated protein phosphatase-1; mkp-1 phosphatase; mkp 1 phosphatase; map phosphatase-1; map phosphatase 1;

MeSH Related Number : EC 3.1.3.18;

Registry Number MeSH : EC 3.1.3.48;

Is substance : O;

UNII : EC 3.1.3.48;

Details

Origin ID

D054638;

UMLS CUI

C0096069;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- Cyclin-Dependent Kinase Inhibitor 3 [NCIt concept]
- Dual-specificity phosphatase 1 [OMIM gene]
- Eyes Absent Homolog 1 [NCIt concept]
- Low Molecular Weight Phosphotyrosine Protein Phosphatase [NCIt concept]
- M-Phase Inducer Phosphatase 1 [NCIt concept]
- dual specificity phosphatase 1 [HGNC gene]
Record concept(s)
- dual specificity phosphatase 1 [MeSH concept]
Related MeSH Supplementary Concept(s)
- DUSP1 protein, human [MeSH Supplementary Concept]
- Dusp1 protein, mouse [MeSH Supplementary Concept]
- Dusp1 protein, rat [MeSH Supplementary Concept]
- Mkp protein, Drosophila [MeSH Supplementary Concept]
- Pmp1 protein, S pombe [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]

Keyword's position in hierarchy(ies) :

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