protein tyrosine phosphatase, Non-Receptor type 1

Preferred Label : protein tyrosine phosphatase, Non-Receptor type 1;

MeSH definition : A subtype of non-receptor protein tyrosine phosphatases that includes two distinctive targeting motifs; an N-terminal motif specific for the INSULIN RECEPTOR, and a C-terminal motif specific for the SH3 domain containing proteins. This subtype includes a hydrophobic domain which localizes it to the ENDOPLASMIC RETICULUM.;

MeSH synonym : protein tyrosine phosphatase 1b; protein-tyrosine phosphatase ha2; ptpase ha2; ptpase 1b; protein tyrosine phosphatase ha2; protein tyrosine phosphatase, non receptor type 1;

Registry Number MeSH : EC 3.1.3.48;

Is substance : O;

UNII : EC 3.1.3.48;

Details

Origin ID

D054562;

UMLS CUI

C0908145;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- Cyclin-Dependent Kinase Inhibitor 3 [NCIt concept]
- Dual Specificity Protein Phosphatase 1 [NCIt concept]
- Dual Specificity Protein Phosphatase 3 [NCIt concept]
- Eyes Absent Homolog 1 [NCIt concept]
- Low Molecular Weight Phosphotyrosine Protein Phosphatase [NCIt concept]
- M-Phase Inducer Phosphatase 1 [NCIt concept]
- PTPN1 wt Allele [NCIt concept]
- protein tyrosine phosphatase non-receptor type 1 [HGNC gene]
Currated CISMeF NLP mapping
- Tyrosine-Protein Phosphatase Non-Receptor Type 1 [NCIt concept]
Indexing information
- (((5-(1,1-dimethylethyl)thiazol-2-yl)methyl)(((4-(4-(4-(1-propylbutyl)phenoxy)methyl)phenyl)thiazol-2-yl)methyl)amino)acetic acid [MeSH Supplementary Concept]
- 2-(2-carboxybenzoylamino)-4-(3'-chloro-4'-fluorobiphenyl-4-yl)thiophene-3-carboxylic acid ethyl ester [MeSH Supplementary Concept]
- 3,4,3',4'-tetrahydroxy-9,7'beta-epoxylignano-7beta,9'-lactone [MeSH Supplementary Concept]
- 3,4-dibromo-5-(2-bromo-3,4-dihydroxy-6-(isobutoxymethyl)benzyl)benzene-1,2-diol [MeSH Supplementary Concept]
- 3-bromo-4,5-bis(2,3-dibromo-4,5-dihydroxybenzyl)-1,2-benzenediol [MeSH Supplementary Concept]
- 3-oxo-28-(phthaloyl-4')erythrane [MeSH Supplementary Concept]
- 4-((5-(4-benzyloxybenzylidene)-2-(4-trifluoromethylphenylimino)-4-oxo-3-thiazolidinyl)methyl)benzoic acid [MeSH Supplementary Concept]
- CCF 06240 [MeSH Supplementary Concept]
- ilekudinol A [MeSH Supplementary Concept]
- methyl sarcotroate A [MeSH Supplementary Concept]
- methyl sarcotroate B [MeSH Supplementary Concept]
- postinin A [MeSH Supplementary Concept]
- postinin B [MeSH Supplementary Concept]
- ratanhiaphenol III [MeSH Supplementary Concept]
- trans-(3)E-3-(3,4-dihydroxybenzylidene)-5-(3,4-dihydroxyphenyl)-4-(hydroxymethyl)dihydrofuran-2(3H)-one [MeSH Supplementary Concept]
Record concept(s)
- protein tyrosine phosphatase, Non-Receptor type 1 [MeSH concept]
Related MeSH Supplementary Concept(s)
- PTPN1 protein, human [MeSH Supplementary Concept]
- Ptpn1 protein, mouse [MeSH Supplementary Concept]
- Ptpn1 protein, rat [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]

Keyword's position in hierarchy(ies) :

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