nicotinamide phosphoribosyltransferase

Preferred Label : nicotinamide phosphoribosyltransferase;

MeSH definition : An enzyme that catalyzes the formation of nicotinamide mononucleotide (NMN) from nicotinamide and 5-phosphoribosyl-1-pyrophosphate, the rate-limiting step in the biosynthesis of the NAD coenzyme. It is also known as a growth factor for early B-LYMPHOCYTES, or an ADIPOKINE with insulin-mimetic effects (visfatin).;

MeSH synonym : colony-enhancing factor, pre-b-cell; nampt protein; phosphoribosyltransferase, nicotinamide; pre b cell colony enhancing factor; visfatin; Pre-B-Cell Colony-Enhancing Factor; NAmPRTase; NMN Pyrophosphorylase;

MeSH Related Number : 9030-27-7 (CRN);

Registry Number MeSH : EC 2.4.2.12;

Wikipedia link : https://en.wikipedia.org/wiki/Nicotinamide phosphoribosyltransferase;

Is substance : O;

UNII : EC 2.4.2.12;

Details

Origin ID

D054409;

UMLS CUI

C0068707;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Indexing information
- CB 30865 [MeSH Supplementary Concept]
- N-(4-((1-propyl-1H-pyrazol-4-yl)sulfonyl)phenyl)-2-(pyridin-3-yl)cyclopropanecarboxamide [MeSH Supplementary Concept]
- TP 201565 [MeSH Supplementary Concept]
Record concept(s)
- nicotinamide phosphoribosyltransferase [MeSH concept]
Related MeSH Supplementary Concept(s)
- nicotinamide phosphoribosyltransferase, human [MeSH Supplementary Concept]
- nicotinamide phosphoribosyltransferase, mouse [MeSH Supplementary Concept]
- nicotinamide phosphoribosyltransferase, rat [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- Nicotinamide phosphoribosyltransferase (substance) [SNOMED CT concept]
- nicotinamide phosphoribosyltransferase [SNOMED Notion]

Keyword's position in hierarchy(ies) :

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