DNA fragmentation

Preferred Label : DNA fragmentation;

MeSH definition : Splitting the DNA into shorter pieces by endonucleolytic DNA CLEAVAGE at multiple sites. It includes the internucleosomal DNA fragmentation, which along with chromatin condensation, are considered to be the hallmarks of APOPTOSIS.;

MeSH synonym : fragmentation, dna;

MeSH hyponym : DNA degradation, apoptotic; Apoptotic DNA Degradation;

MeSH annotation : if apoptotic, coordinate with APOPTOSIS;

Details

Origin ID

D053938;

UMLS CUI

C0376669;

Allowable qualifiers
- drug effects [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
Currated CISMeF NLP mapping
- DNA Fragmentation [NCIt concept]
Indexing information
- CIDEB protein, human [MeSH Supplementary Concept]
- Drep2 protein, Drosophila [MeSH Supplementary Concept]
- Drep3 protein, Drosophila [MeSH Supplementary Concept]
- caspase-activated DNase inhibitor [MeSH Supplementary Concept]
- cidea protein, mouse [MeSH Supplementary Concept]
- cideb protein, mouse [MeSH Supplementary Concept]
Record concept(s)
- DNA degradation, apoptotic [MeSH concept]
- DNA fragmentation [MeSH concept]
See also
- dna degradation, necrotic [MeSH Descriptor]
See also (suggested by CISMeF)
- in situ nick-end labeling [MeSH Descriptor]
Semantic type(s)
- Molecular Function [UMLS semantic type]
UMLS correspondences (same concept)
- DNA Fragmentation [NCIt concept]
Validated automatic mappings to BTNT
- apoptotic DNA fragmentation [GO term]

Keyword's position in hierarchy(ies) :

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