oncostatin M - CISMeF

Preferred Label : oncostatin M;

MeSH definition : A cytokine with both pro- and anti-inflammatory actions that depend upon the cellular microenvironment. Oncostatin M is a 28 kDa monomeric glycoprotein that is similar in structure to LEUKEMIA INHIBITORY FACTOR. Its name derives from the the observation that it inhibited the growth of tumor cells and augmented the growth of normal fibroblasts.;

MeSH CAS label : oncostatin M;

Registry Number MeSH : 106956-32-5;

Is substance : O;

Details

Origin ID

D053683;

UMLS CUI

C0069535;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- Oncostatin M [OMIM gene]
- Oncostatin M Measurement [NCIt concept]
- oncostatin M [HGNC gene]
- oncostatin-M receptor binding [GO term]
Currated CISMeF NLP mapping
- Oncostatin-M [NCIt concept]
Pharmacological action(s)
- antineoplastic agents [MeSH Descriptor]
- growth inhibitors [MeSH Descriptor]
Record concept(s)
- oncostatin M [MeSH concept]
Related MeSH Supplementary Concept(s)
- OSM protein, human [MeSH Supplementary Concept]
- osm protein, mouse [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Oncostatin-M [NCIt concept]

Keyword's position in hierarchy(ies) :

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