epithelial sodium channels

Preferred Label : epithelial sodium channels;

MeSH definition : Sodium channels found on salt-reabsorbing EPITHELIAL CELLS that line the distal NEPHRON; the distal COLON; SALIVARY DUCTS; SWEAT GLANDS; and the LUNG. They are AMILORIDE-sensitive and play a critical role in the control of sodium balance, BLOOD VOLUME, and BLOOD PRESSURE.;

MeSH synonym : epithelial amiloride sensitive sodium channel; enac (epithelial na channel); sodium channel, epithelial; epithelial amiloride-sensitive sodium channel; sodium channels, epithelial; epithelial sodium ion channels; epithelial sodium channel;

MeSH hyponym : subunit, scnn1 alpha; beta subunit, scnn1; gamma subunit, scnn1; delta subunit, scnn1; subunit, scnn1 beta; epithelial sodium channel, beta subunit; epithelial sodium channel, alpha subunit; epithelial sodium channel, gamma subunit; epithelial sodium channel, delta subunit; Sodium Channel, Nonvoltage-gated 1 Protein, gamma Subunit; ENaC gamma; SCNN1 gamma Subunit; ENaC delta; Sodium Channel, Nonvoltage-gated 1 Protein, delta Subunit; SCNN1 delta Subunit; Sodium Channel, Nonvoltage-gated 1 Protein, alpha Subunit; ENaC alpha; SCNN1 alpha Subunit; alpha Subunit, SCNN1; Sodium Channel, Nonvoltage-gated 1 Protein, beta Subunit; ENaC beta; SCNN1 beta Subunit;

Wikipedia link : https://en.wikipedia.org/wiki/Epithelial sodium channels;

Is substance : O;

Details

Origin ID

D053503;

UMLS CUI

C0384156;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- Sodium channel, epithelial 1, alpha subunit [OMIM gene]
- Sodium channel, epithelial 1, beta subunit [OMIM gene]
- Sodium channel, epithelial 1, delta subunit [OMIM gene]
- Sodium channel, epithelial 1, gamma subunit [OMIM gene]
- ligand-gated sodium channel activity [GO term]
Record concept(s)
- epithelial sodium channel, alpha subunit [MeSH concept]
- epithelial sodium channel, beta subunit [MeSH concept]
- epithelial sodium channel, delta subunit [MeSH concept]
- epithelial sodium channel, gamma subunit [MeSH concept]
- epithelial sodium channels [MeSH concept]
Related MeSH Supplementary Concept(s)
- ACD-1 protein, C elegans [MeSH Supplementary Concept]
- PPK26 protein, Drosophila [MeSH Supplementary Concept]
- PPK28 protein, drosophila [MeSH Supplementary Concept]
- SCNN1A protein, human [MeSH Supplementary Concept]
- SCNN1B protein, human [MeSH Supplementary Concept]
- SCNN1D protein, human [MeSH Supplementary Concept]
- SCNN1G protein, human [MeSH Supplementary Concept]
- Scnn1a protein, mouse [MeSH Supplementary Concept]
- Scnn1a protein, rat [MeSH Supplementary Concept]
- Scnn1b protein, mouse [MeSH Supplementary Concept]
- Scnn1b protein, rat [MeSH Supplementary Concept]
- Scnn1g protein, mouse [MeSH Supplementary Concept]
- Scnn1g protein, rat [MeSH Supplementary Concept]
- bronchiectasis with or without elevated sweat chloride 1 [MeSH Supplementary Concept]
- bronchiectasis with or without elevated sweat chloride 3 [MeSH Supplementary Concept]
Related MeSH term(s)
- epithelial sodium channel agonists [MeSH Descriptor]
- epithelial sodium channel blockers [MeSH Descriptor]
See also
- liddle syndrome [MeSH Descriptor]
- pseudohypoaldosteronism [MeSH Descriptor]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]

Keyword's position in hierarchy(ies) :

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