receptors, notch

Preferred Label : receptors, notch;

MeSH definition : A family of conserved cell surface receptors that contain EPIDERMAL GROWTH FACTOR repeats in their extracellular domain and ANKYRIN repeats in their cytoplasmic domains. The cytoplasmic domain of notch receptors is released upon ligand binding and translocates to the CELL NUCLEUS where it acts as transcription factor.; A family of conserved cell surface receptors that contain EPIDERMAL GROWTH FACTOR repeats in their extracellular domain and ANKYRIN REPEATS in their cytoplasmic domains. The cytoplasmic domains are released upon ligand binding and translocate to the CELL NUCLEUS, where they act as transcription factors.;

MeSH synonym : notch proteins; notch receptors; Notch Protein; Protein, Notch; Notch Receptor; Receptor, Notch;

Wikipedia link : https://en.wikipedia.org/wiki/Notch protein;

Is substance : O;

Details

Origin ID

D051880;

UMLS CUI

C0083792;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- physiology [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- Notch Family [NCIt concept]
Record concept(s)
- receptors, notch [MeSH concept]
Related MeSH Supplementary Concept(s)
- Glp-1 protein, C elegans [MeSH Supplementary Concept]
- Lin-12 protein, C elegans [MeSH Supplementary Concept]
- N protein, Drosophila [MeSH Supplementary Concept]
- NOTCH1 protein, Xenopus [MeSH Supplementary Concept]
- NOTCH3 protein, human [MeSH Supplementary Concept]
- NOTCH4 protein, human [MeSH Supplementary Concept]
- Notch3 protein, mouse [MeSH Supplementary Concept]
- Notch3 protein, rat [MeSH Supplementary Concept]
- Notch3 protein, zebrafish [MeSH Supplementary Concept]
- Notch4 protein, mouse [MeSH Supplementary Concept]
- Notch4 protein, rat [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Receptor [UMLS semantic type]
UMLS correspondences (same concept)
- Notch Family [NCIt concept]

Keyword's position in hierarchy(ies) :

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