complement C3 convertase, alternative pathway

Preferred Label : complement C3 convertase, alternative pathway;

MeSH definition : A serine protease that is the complex of COMPLEMENT C3B and COMPLEMENT FACTOR BB. It cleaves multiple COMPLEMENT C3 into COMPLEMENT C3A (anaphylatoxin) and COMPLEMENT C3B in the ALTERNATIVE COMPLEMENT ACTIVATION PATHWAY.;

MeSH synonym : alternative pathway c3 convertase; complement 3 convertase, alternative pathway; c3 convertase (c3bbb); c3 convertase, alternative pathway; complement 3b-associated factor b-fragment bb; complement 3b associated factor b fragment bb;

Related MeSH term : complement C3 convertase, CVFBb; CVFBb;

MeSH Related Number : complement C3 convertase, CVFBb; EC 3.4.21.47;

Registry Number MeSH : EC 3.4.21.47;

Related CAS MeSH : EC 3.4.21.47 (Complement C3 convertase, CVFBb);

Wikipedia link : https://en.wikipedia.org/wiki/Complement c3 convertase, alternative pathway;

Is substance : O;

UNII : EC 3.4.21.47;

Details

Origin ID

D051561;

UMLS CUI

C1564374;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- Active C3bBb (substance) [SNOMED CT concept]
- active c3bbb [SNOMED Notion]
- obsolete alternative-complement-pathway C3/C5 convertase activity [GO term]
Pharmacological action(s)
- immunologic factors [MeSH Descriptor]
Record concept(s)
- complement C3 convertase, CVFBb [MeSH concept]
- complement C3 convertase, alternative pathway [MeSH concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
UMLS correspondences (same concept)
- Active C3bBb (substance) [SNOMED CT concept]
- active c3bbb [SNOMED Notion]

Keyword's position in hierarchy(ies) :

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