" /> receptor, fibroblast growth factor, type 2 - CISMeF





Preferred Label : receptor, fibroblast growth factor, type 2;

MeSH definition : A fibroblast growth factor receptor that is found in two isoforms. One receptor isoform is found in the MESENCHYME and is activated by FIBROBLAST GROWTH FACTOR 2. A second isoform of fibroblast growth factor receptor 2 is found mainly in EPITHELIAL CELLS and is activated by FIBROBLAST GROWTH FACTOR 7 and FIBROBLAST GROWTH FACTOR 10. Mutation of the gene for fibroblast growth factor receptor 2 can result in craniosynostotic syndromes (e.g., APERT SYNDROME; and CROUZON SYNDROME).; A fibroblast growth factor receptor which contains three extracellular IMMUNOGLOBULIN I-SET DOMAINS and is expressed as two isoforms. One receptor isoform is expressed in the MESENCHYME and is activated by FIBROBLAST GROWTH FACTOR 2. A second isoform is expressed mainly by EPITHELIAL CELLS and is activated by FIBROBLAST GROWTH FACTOR 7 and FIBROBLAST GROWTH FACTOR 10. Mutation of the gene for fibroblast growth factor receptor 2 can result in craniosynostotic syndromes (e.g., APERT SYNDROME; and CROUZON SYNDROME).;

MeSH synonym : bek fibroblast growth factor receptor; bek protein tyrosine kinase; bek-related fibroblast growth factor-receptor-1; fibroblast growth factor receptors 2; bek fibroblast growth factor receptor kinase; fgfr2 protein; fibroblast growth factor receptor 2; bek fgf receptor kinase; bek related fibroblast growth factor receptor 1; CD332 Antigen; Antigen, CD332;

CISMeF synonym : EC 2.7.1.112;

MeSH hyponym : fibroblast growth factor receptor 2b; fibroblast growth factor receptor 2c; Receptor, Fibroblast Growth Factor 2c; FGFR2c; Receptor, Fibroblast Growth Factor 2b; FGFR2b; Fibroblast Growth Factor Receptors 2b;

MeSH Related Number : fibroblast growth factor receptor 2c; fibroblast growth factor receptor 2b; EC 2.7.10.1;

Registry Number MeSH : EC 2.7.10.1;

Related CAS MeSH : EC 2.7.10.1 (Fibroblast growth factor receptor 2b); EC 2.7.10.1 (Fibroblast growth factor receptor 2c);

Is substance : O;

UNII : EC 2.7.10.1;

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A fibroblast growth factor receptor that is found in two isoforms. One receptor isoform is found in the MESENCHYME and is activated by FIBROBLAST GROWTH FACTOR 2. A second isoform of fibroblast growth factor receptor 2 is found mainly in EPITHELIAL CELLS and is activated by FIBROBLAST GROWTH FACTOR 7 and FIBROBLAST GROWTH FACTOR 10. Mutation of the gene for fibroblast growth factor receptor 2 can result in craniosynostotic syndromes (e.g., APERT SYNDROME; and CROUZON SYNDROME).
A fibroblast growth factor receptor which contains three extracellular IMMUNOGLOBULIN I-SET DOMAINS and is expressed as two isoforms. One receptor isoform is expressed in the MESENCHYME and is activated by FIBROBLAST GROWTH FACTOR 2. A second isoform is expressed mainly by EPITHELIAL CELLS and is activated by FIBROBLAST GROWTH FACTOR 7 and FIBROBLAST GROWTH FACTOR 10. Mutation of the gene for fibroblast growth factor receptor 2 can result in craniosynostotic syndromes (e.g., APERT SYNDROME; and CROUZON SYNDROME).

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08/05/2024


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