receptor, fibroblast growth factor, type 1

Preferred Label : receptor, fibroblast growth factor, type 1;

MeSH definition : A fibroblast growth factor receptor with specificity for FIBROBLAST GROWTH FACTORS; HEPARAN SULFATE PROTEOGLYCAN; and NEURONAL CELL ADHESION MOLECULES. Several variants of the receptor exist due to multiple ALTERNATIVE SPLICING of its mRNA. Fibroblast growth factor receptor 1 is a tyrosine kinase that transmits signals through the MAP KINASE SIGNALING SYSTEM.; A fibroblast growth factor receptor with specificity for FIBROBLAST GROWTH FACTORS; HEPARAN SULFATE PROTEOGLYCAN; and NEURONAL CELL ADHESION MOLECULES. Several variants of the receptor exist due to multiple ALTERNATIVE SPLICING of its mRNA. Fibroblast growth factor receptor 1 contains three extracellular IMMUNOGLOBULIN C2-SET DOMAINS and is a tyrosine kinase that transmits signals through the MAP KINASE SIGNALING SYSTEM.;

MeSH synonym : fibroblast growth factor receptor 1; fms-like tyrosine kinase-2; fms like tyrosine kinase 2; fgfr1 protein; fgfr1 tyrosine kinase; CD331 Antigen; Antigen, CD331;

CISMeF synonym : EC 2.7.1.112;

MeSH hyponym : fibroblast growth factor soluble receptor 1;

Registry Number MeSH : EC 2.7.10.1;

Wikipedia link : https://en.wikipedia.org/wiki/Receptor, fibroblast growth factor, type 1;

Is substance : O;

UNII : EC 2.7.10.1;

Details

Origin ID

D051496;

UMLS CUI

C0170936;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- physiology [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
Indexing information
- 1-(2-chloro-4-((5-methyl-5H-pyrrolo(3,2-d)pyrimidin-4-yl)oxy)phenyl)-3-(4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)urea [MeSH Supplementary Concept]
- NP 603 [MeSH Supplementary Concept]
- ethyl 8-oxo-8H-acenaphtho(1,2-b)pyrrole-9-carboxylate [MeSH Supplementary Concept]
- infigratinib [MeSH Supplementary Concept]
Record concept(s)
- fibroblast growth factor soluble receptor 1 [MeSH concept]
- receptor, fibroblast growth factor, type 1 [MeSH concept]
Related MeSH Supplementary Concept(s)
- CEP110-FGFR1 fusion protein, human [MeSH Supplementary Concept]
- FGFR1 protein, human [MeSH Supplementary Concept]
- FGFR1 protein, strongylocentrotus purpuratus [MeSH Supplementary Concept]
- FP-1039 [MeSH Supplementary Concept]
- Fgfr1 protein, mouse [MeSH Supplementary Concept]
- Fgfr1 protein, rat [MeSH Supplementary Concept]
- fgfr1a protein, zebrafish [MeSH Supplementary Concept]
See also
- kallmann syndrome [MeSH Descriptor]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
- Receptor [UMLS semantic type]

Keyword's position in hierarchy(ies) :

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