Toll-Like receptors

Preferred Label : Toll-Like receptors;

MeSH definition : A family of pattern recognition receptors characterized by an extracellular leucine-rich domain and a cytoplasmic domain that share homology with the INTERLEUKIN 1 RECEPTOR and the DROSOPHILA toll protein. Following pathogen recognition, toll-like receptors recruit and activate a variety of SIGNAL TRANSDUCING ADAPTOR PROTEINS.;

MeSH synonym : receptors, toll-like; toll-like receptor; receptor, toll-like; toll like receptor; receptors, toll like; toll like receptors;

MeSH annotation : general; prefer specifics;

Wikipedia link : https://en.wikipedia.org/wiki/Toll-like receptor;

Is substance : O;

Details

Origin ID

D051193;

UMLS CUI

C0670896;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- physiology [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- Toll-like receptor [COVID-19 Thesaurus concept]
Indexing information
- DIMS0150 [MeSH Supplementary Concept]
- NRROS protein, human [MeSH Supplementary Concept]
- gardiquimod [MeSH Supplementary Concept]
Record concept(s)
- Toll-Like receptors [MeSH concept]
Related MeSH Supplementary Concept(s)
- TLR11 protein, human [MeSH Supplementary Concept]
- Tlr11 protein, mouse [MeSH Supplementary Concept]
- Tlr12 protein, mouse [MeSH Supplementary Concept]
- Tlr13 protein, mouse [MeSH Supplementary Concept]
- Toll-9 protein, drosophila [MeSH Supplementary Concept]
- tl protein, drosophila [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Receptor [UMLS semantic type]

Keyword's position in hierarchy(ies) :

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