Isovaleryl-CoA dehydrogenase

Preferred Label : Isovaleryl-CoA dehydrogenase;

MeSH definition : A mitochondrial flavoprotein, this enzyme catalyzes the oxidation of 3-methylbutanoyl-CoA to 3-methylbut-2-enoyl-CoA using FAD as a cofactor. Defects in the enzyme, is associated with isovaleric acidemia (IVA).;

MeSH synonym : dehydrogenase, isovaleryl-coenzyme a; isovaleryl-coenzyme a dehydrogenase; coa dehydrogenase, isovaleryl; dehydrogenase, isovaleryl-coa; dehydrogenase, isovaleryl coa; isovaleryl coenzyme a dehydrogenase; isovaleryl CoA dehydrogenase;

CISMeF synonym : a dehydrogenase, isovaleryl-coenzyme;

MeSH Related Number : 37274-61-6 (CRN);

Registry Number MeSH : EC 1.3.99.10; EC 1.3.8.4;

Is substance : O;

UNII : EC 1.3.8.4;

Details

Origin ID

D050769;

UMLS CUI

C0064095;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- Isovaleryl-CoA Dehydrogenase, Mitochondrial [NCIt concept]
- Isovaleryl-coa dehydrogenase [OMIM gene]
- Isovaleryl-coenzyme A dehydrogenase (substance) [SNOMED CT concept]
- isovaleryl-CoA dehydrogenase [HGNC gene]
- isovaleryl-CoA dehydrogenase [ORDO Gene]
- isovaleryl-coa dehydrogenase [SNOMED Notion]
Record concept(s)
- Isovaleryl-CoA dehydrogenase [MeSH concept]
Related MeSH Supplementary Concept(s)
- acidemia, isovaleric [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- Isovaleryl-coenzyme A dehydrogenase (substance) [SNOMED CT concept]
- isovaleryl-coa dehydrogenase [SNOMED Notion]

Keyword's position in hierarchy(ies) :

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