protoporphyrinogen oxidase

Preferred Label : protoporphyrinogen oxidase;

MeSH definition : A membrane-bound flavoenzyme that catalyzes the oxygen-dependent aromatization of protoporphyrinogen IX (Protogen) to protoporphyrin IX (Proto IX). It is the last enzyme of the common branch of the HEME and CHLOROPHYLL pathways in plants, and is the molecular target of diphenyl ether-type herbicides. VARIEGATE PORPHYRIA is an autosomal dominant disorder associated with deficiency of protoporphyrinogen oxidase.;

MeSH synonym : protoporphyrinogen ix oxidase; protoporphyrinogenase; oxidase, protoporphyrinogen; protox; protoporphyrinogen dehydrogenase; dehydrogenase, protoporphyrinogen; oxidase, protoporphyrinogen ix;

Registry Number MeSH : EC 1.3.3.4;

Is substance : O;

UNII : EC 1.3.3.4;

Details

Origin ID

D050768;

UMLS CUI

C0072500;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Record concept(s)
- protoporphyrinogen oxidase [MeSH concept]
Related MeSH Supplementary Concept(s)
- AT5G14220 protein, Arabidopsis [MeSH Supplementary Concept]
- HEM14 protein, S cerevisiae [MeSH Supplementary Concept]
- HemG protein, E coli [MeSH Supplementary Concept]
- PPO1 protein, Arabidopsis [MeSH Supplementary Concept]
- PPOX protein, human [MeSH Supplementary Concept]
- ppox protein, mouse [MeSH Supplementary Concept]
Related MeSH term(s)
- porphyria, variegate [MeSH Descriptor]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- Protoporphyrinogen oxidase (substance) [SNOMED CT concept]
- protoporphyrinogen oxidase [SNOMED Notion]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients