crk-associated substrate protein

Preferred Label : crk-associated substrate protein;

MeSH definition : Crk-associated substrate was originally identified as a highly phosphorylated 130 kDa protein that associates with ONCOGENE PROTEIN CRK and ONCOGENE PROTEIN SRC. It is a signal transducing adaptor protein that undergoes tyrosine PHOSPHORYLATION in signaling pathways that regulate CELL MIGRATION and CELL PROLIFERATION.; A highly phosphorylated 130 kDa protein that associates with ONCOGENE PROTEIN CRK and ONCOGENE PROTEIN SRC. It undergoes tyrosine PHOSPHORYLATION in signaling pathways that regulate CELL MIGRATION and CELL PROLIFERATION.;

MeSH synonym : breast cancer anti estrogen resistance 1 protein; crk-associated substrate; p130cas protein; breast cancer anti-estrogen resistance 1 protein; p130 cas protein; p130 crk-associated substrate; p130 crk associated substrate; bcar1 protein; crk associated substrate; crk associated substrate protein; BCAR1 p130Cas Protein; Protein, BCAR1 p130Cas; p130Cas Protein, BCAR1; CRKAS Protein; Protein, CRKAS;

CISMeF synonym : cas protein, p130; ckras protein; crk-associated substrate, p130; substrate protein, crk-associated; substrate, p130 crk-associated;

Is substance : O;

Details

Origin ID

D050719;

UMLS CUI

C0961232;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- BCAR1 scaffold protein, Cas family member [HGNC gene]
- Bcar1 scaffold protein, cas family member [OMIM gene]
- Breast Cancer Anti-Estrogen Resistance Protein 1 [NCIt concept]
- GTPase KRas [NCIt concept]
Indexing information
- NEDD9 protein, human [MeSH Supplementary Concept]
Record concept(s)
- Crk-Associated substrate protein [MeSH concept]
Related MeSH Supplementary Concept(s)
- BCAR1 protein, human [MeSH Supplementary Concept]
- Bcar1 protein, mouse [MeSH Supplementary Concept]
- Bcar1 protein, rat [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]

Keyword's position in hierarchy(ies) :

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