2-oxoisovalerate dehydrogenase (acylating)

Preferred Label : 2-oxoisovalerate dehydrogenase (acylating);

MeSH definition : An NAD dependent enzyme that catalyzes the oxidation 3-methyl-2-oxobutanoate to 2-methylpropanoyl-CoA. It plays a role in the degradation of VALINE; LEUCINE; and ISOLEUCINE.;

MeSH synonym : dehydrogenase, alpha-ketoisovalerate; dehydrogenase, 2-oxoisovalerate; 2-oxoisovalerate dehydrogenase; alpha-ketoisovalerate dehydrogenase; alpha ketoisovalerate dehydrogenase; 2 oxoisovalerate dehydrogenase;

MeSH Related Number : 37211-61-3 (CRN);

Registry Number MeSH : EC 1.2.1.25;

Is substance : O;

UNII : EC 1.2.1.25;

Details

Origin ID

D050645;

UMLS CUI

C0046493;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- 2-oxoisovalerate dehydrogenase (acylating) [SNOMED Notion]
- 2-oxoisovalerate dehydrogenase (acylating) (substance) [SNOMED CT concept]
- 2-oxoisovalerate dehydrogenase (lipoamide) (substance) [SNOMED CT concept]
Record concept(s)
- 2-Oxoisovalerate dehydrogenase (Acylating) [MeSH concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- 2-oxoisovalerate dehydrogenase (acylating) [SNOMED Notion]
- 2-oxoisovalerate dehydrogenase (acylating) (substance) [SNOMED CT concept]

Keyword's position in hierarchy(ies) :

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