Preferred Label : snare proteins;
MeSH definition : A superfamily of small proteins which are involved in the MEMBRANE FUSION events,
intracellular protein trafficking and secretory processes. They share a homologous
SNARE motif. The SNARE proteins are divided into subfamilies: QA-SNARES; QB-SNARES;
QC-SNARES; and R-SNARES. The formation of a SNARE complex (composed of one each of
the four different types SNARE domains (Qa, Qb, Qc, and R)) mediates MEMBRANE FUSION.
Following membrane fusion SNARE complexes are dissociated by the NSFs (N-ETHYLMALEIMIDE-SENSITIVE
FACTORS), in conjunction with SOLUBLE NSF ATTACHMENT PROTEIN, i.e., SNAPs (no relation
to SNAP 25.);
MeSH synonym : nsf attachment protein receptor; receptor, snap; snap receptor; snap receptors; snare; snares; soluble n-ethylmaleimide-sensitive-factor attachment protein receptor; soluble n ethylmaleimide sensitive factor attachment protein receptor; SNARE Protein; Protein, SNARE;
MeSH hyponym : vesicle SNARE proteins; target membrane SNARE proteins; Target SNARE Proteins; SNARE Proteins, Target; tSNAREs; t-SNARE; SNARE Proteins, Vesicle; v-SNAREs; v SNAREs; Vesicular SNARE Proteins; SNARE Proteins, Vesicular; v-SNARE;
Is substance : O;
Origin ID : D050600;
UMLS CUI : C0300824;
Allowable qualifiers
Automatic exact mappings (from CISMeF team)
Currated CISMeF NLP mapping
Record concept(s)
Related MeSH Supplementary Concept(s)
Semantic type(s)
UMLS correspondences (same concept)
A superfamily of small proteins which are involved in the MEMBRANE FUSION events,
intracellular protein trafficking and secretory processes. They share a homologous
SNARE motif. The SNARE proteins are divided into subfamilies: QA-SNARES; QB-SNARES;
QC-SNARES; and R-SNARES. The formation of a SNARE complex (composed of one each of
the four different types SNARE domains (Qa, Qb, Qc, and R)) mediates MEMBRANE FUSION.
Following membrane fusion SNARE complexes are dissociated by the NSFs (N-ETHYLMALEIMIDE-SENSITIVE
FACTORS), in conjunction with SOLUBLE NSF ATTACHMENT PROTEIN, i.e., SNAPs (no relation
to SNAP 25.)