Preferred Label : complement C3-C5 convertases;
MeSH definition : Serine proteases that cleave COMPLEMENT C3 into COMPLEMENT C3A and COMPLEMENT C3B,
or cleave COMPLEMENT C5 into COMPLEMENT C5A and COMPLEMENT C5B. These include the
different forms of C3/C5 convertases in the classical and the alternative pathways
of COMPLEMENT ACTIVATION. Both cleavages take place at the C-terminal of an ARGININE
residue.;
MeSH synonym : c3-c5 convertases, complement; convertase, c3-c5; convertases, complement c3-c5; c3-c5 convertase; c3 c5 convertase; complement C3 C5 convertases;
MeSH hyponym : complement C5 convertases; complement C3 convertases; C3 Convertases, Complement; Convertases, Complement C3; Complement 3 Convertase; Convertase, Complement 3; C3 Convertase; Convertase, C3; C3 Activator; Activator, C3; C 3 Convertase; Convertase, C 3; C5 Convertases, Complement; Convertases, Complement C5; C5 Convertase; C5 Cleaving Enzyme; Complement 5 Convertase;
MeSH Related Number : complement C3 convertases; complement C5 convertases;
Registry Number MeSH : EC 3.4.21.-;
Related CAS MeSH : EC 3.4.21.- (Complement C3 convertases); EC 3.4.21.- (Complement C5 convertases);
Wikipedia link : https://en.wikipedia.org/wiki/C5 convertase;
Is substance : O;
Origin ID : D050577;
UMLS CUI : C1564372;
Allowable qualifiers
- Indexing information
- Pharmacological action(s)
- Record concept(s)
- Semantic type(s)
Serine proteases that cleave COMPLEMENT C3 into COMPLEMENT C3A and COMPLEMENT C3B,
or cleave COMPLEMENT C5 into COMPLEMENT C5A and COMPLEMENT C5B. These include the
different forms of C3/C5 convertases in the classical and the alternative pathways
of COMPLEMENT ACTIVATION. Both cleavages take place at the C-terminal of an ARGININE
residue.
