protease la - CISMeF

Preferred Label : protease la;

MeSH definition : A prokaryotic ATP-dependent protease that plays a role in the degradation of many abnormal proteins. It is a tetramer of 87-kDa subunits, each of which contains a proteolytic site and a ATP-binding site.;

MeSH synonym : endopeptidase la; lon protease;

MeSH Related Number : EC 3.4.21.53;

Registry Number MeSH : EC 3.4.21.53;

Is substance : O;

UNII : EC 3.4.21.53;

Details

Origin ID

D049070;

UMLS CUI

C0207564;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- Endopeptidase [NCIt concept]
- Endopeptidase (substance) [SNOMED CT concept]
- Endopeptidase La (substance) [SNOMED CT concept]
- obsolete endopeptidase La activity [GO term]
- proteases [IUPAC Term]
Record concept(s)
- protease la [MeSH concept]
Related MeSH Supplementary Concept(s)
- lon protein, E coli [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- Endopeptidase La (substance) [SNOMED CT concept]

Keyword's position in hierarchy(ies) :

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