3-alpha-hydroxysteroid dehydrogenase (b-specific)

Preferred Label : 3-alpha-hydroxysteroid dehydrogenase (b-specific);

MeSH definition : A 3-hydroxysteroid dehydrogenase which catalyzes the reversible reduction of the active androgen, DIHYDROTESTOSTERONE to 5 ALPHA-ANDROSTANE-3 ALPHA,17 BETA-DIOL. It also has activity towards other 3-alpha-hydroxysteroids and on 9-, 11- and 15- hydroxyprostaglandins. The enzyme is B-specific in reference to the orientation of reduced NAD or NADPH.;

MeSH synonym : 3 alpha hydroxysteroid oxidoreductase; 3 alpha-hydroxysteroid dehydrogenase; 3alpha-hydroxysteroid dehydrogenase (b-specific); 3 alpha-hydroxysteroid oxidoreductase; oxidoreductase, 3 alpha-hydroxysteroid; 3 alpha hydroxysteroid dehydrogenase; dehydrogenase, 3 alpha-hydroxysteroid; 3 alpha-Hydroxysteroid dehydrogenase (B-Specific);

MeSH hyponym : 5 alpha-Dihydroprogesterone 3 alpha-Hydroxysteroid oxidoreductase; 5 alpha Dihydroprogesterone 3 alpha Hydroxysteroid Oxidoreductase; 5-DP-3 alpha-HSO; NADPH-5 alpha-Dihydroprogesterone 3 alpha-Hydroxysteroid Oxidoreductase; NADPH 5 alpha Dihydroprogesterone 3 alpha Hydroxysteroid Oxidoreductase; 5 alpha-3 alpha-Hydroxysteroid Dehydrogenase;

CISMeF hyponym : EC 1.1.1.50;

MeSH Related Number : 5 alpha-Dihydroprogesterone 3 alpha-Hydroxysteroid oxidoreductase; 9028-56-2 (CRN); EC 1.1.1.50;

Registry Number MeSH : EC 1.1.1.50;

Related CAS MeSH : EC 1.1.1.50 (5 alpha-Dihydroprogesterone 3 alpha-Hydroxysteroid oxidoreductase);

Is substance : O;

UNII : EC 1.1.1.50;

Details

Origin ID

D045002;

UMLS CUI

C0048751;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- androsterone dehydrogenase (B-specific) activity [GO term]
Record concept(s)
- 3-alpha-Hydroxysteroid dehydrogenase (B-Specific) [MeSH concept]
- 5 alpha-Dihydroprogesterone 3 alpha-Hydroxysteroid oxidoreductase [MeSH concept]
Related MeSH Supplementary Concept(s)
- AKR1C3 protein, rat [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]

Keyword's position in hierarchy(ies) :

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