Preferred Label : receptor, par-2;
MeSH definition : A G-protein-coupled, proteinase-activated receptor that is expressed in a variety
of tissues including ENDOTHELIUM; LEUKOCYTES; and the GASTROINTESTINAL TRACT. The
receptor is activated by TRYPSIN, which cleaves off the N-terminal peptide from the
receptor. The new N-terminal peptide is a cryptic ligand for the receptor. The uncleaved
receptor can also be activated by the N-terminal peptide present on the activated
THROMBIN RECEPTOR and by small synthetic peptides that contain the unmasked N-terminal
sequence.;
MeSH synonym : receptor, par2; receptor, trypsin; par-2 receptor; par2 receptor; protease activated receptor 2; trypsin receptor; trypsin receptors; receptors, trypsin; proteinase activated receptor 2; par 2 receptor; protease-activated receptor 2; receptor 2, protease-activated; receptor, PAR 2;
Wikipedia link : https://en.wikipedia.org/wiki/Receptor, par-2;
Is substance : O;
Origin ID : D044464;
UMLS CUI : C0259628;
Allowable qualifiers
- Automatic exact mappings (from CISMeF team)
- Indexing information
- K 12940 [MeSH Supplementary Concept]
- Record concept(s)
- Related MeSH Supplementary Concept(s)
- Semantic type(s)
A G-protein-coupled, proteinase-activated receptor that is expressed in a variety
of tissues including ENDOTHELIUM; LEUKOCYTES; and the GASTROINTESTINAL TRACT. The
receptor is activated by TRYPSIN, which cleaves off the N-terminal peptide from the
receptor. The new N-terminal peptide is a cryptic ligand for the receptor. The uncleaved
receptor can also be activated by the N-terminal peptide present on the activated
THROMBIN RECEPTOR and by small synthetic peptides that contain the unmasked N-terminal
sequence.
