Preferred Label : receptor, serotonin, 5-ht1d;
MeSH definition : A serotonin receptor subtype that is localized to the CAUDATE NUCLEUS; PUTAMEN; the
NUCLEUS ACCUMBENS; the HIPPOCAMPUS, and the RAPHE NUCLEI. It plays a role as a terminal
autoreceptor that regulates the rate of SEROTONIN release from nerve endings. This
serotonin receptor subtype is closely related to and has similar drug binding properties
as the 5-HT1B RECEPTOR, but is expressed at low levels. It is particularly sensitive
to the agonist SUMATRIPTAN and may be involved in mediating the drug's antimigrane
effect.;
MeSH synonym : serotonin 1d receptor; receptors, serotonin 1d; 5-hydroxytryptamine1d receptor; 5-ht1d receptor; 5 ht1d receptor; receptor, 5-ht1d; receptor, serotonin 1d; serotonin 1d receptors; 5-ht(1d) receptor; 5 hydroxytryptamine1d receptor; receptor, 5-hydroxytryptamine1d;
MeSH hyponym : 5-HT(1Dalpha) receptor; Serotonin 1Dalpha Receptor; Receptor, Serotonin 1Dalpha; Serotonin 1Dalpha Receptors; Serotonin 1D Alpha Receptor; 5-HT1Dalpha Receptor;
Is substance : O;
Origin ID : D044346;
UMLS CUI : C0530967;
Allowable qualifiers
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A serotonin receptor subtype that is localized to the CAUDATE NUCLEUS; PUTAMEN; the
NUCLEUS ACCUMBENS; the HIPPOCAMPUS, and the RAPHE NUCLEI. It plays a role as a terminal
autoreceptor that regulates the rate of SEROTONIN release from nerve endings. This
serotonin receptor subtype is closely related to and has similar drug binding properties
as the 5-HT1B RECEPTOR, but is expressed at low levels. It is particularly sensitive
to the agonist SUMATRIPTAN and may be involved in mediating the drug's antimigrane
effect.
