Preferred Label : receptor, serotonin, 5-ht1b;
MeSH definition : A serotonin receptor subtype found at high levels in the BASAL GANGLIA and the frontal
cortex. It plays a role as a terminal autoreceptor that regulates the rate of SEROTONIN
release from nerve endings. This serotonin receptor subtype is closely related to
and has similar drug binding properties as the 5-HT1D RECEPTOR. It is particularly
sensitive to the agonist SUMATRIPTAN and may be involved in mediating the drug's antimigraine
effect.;
MeSH synonym : receptor, serotonin 1b; receptor, 5 hydroxytryptamine 1b; receptor, 5-ht1b; receptor, 5-ht1dbeta; receptor, 5-hydroxytryptamine 1b; receptors, 5-hydroxytryptamine 1b; serotonin 1b receptor; serotonin 1d beta receptor; 1b receptor, 5-hydroxytryptamine; 1b receptors, 5-hydroxytryptamine; 5 ht1b receptor; 5 hydroxytryptamine 1b receptor; 5 hydroxytryptamine 1b receptors; 5-ht1b receptor; 5-hydroxytryptamine 1b receptor; 5-hydroxytryptamine 1b receptors; receptor, serotonin 1dbeta; 5-ht(1b) receptor; 5-ht(1dbeta) receptor; 5-ht1dbeta receptor; 5 ht1dbeta receptor; receptor, serotonin type 1dbeta; serotonin 1dbeta receptors; receptors, serotonin 1dbeta; serotonin 1dbeta receptor;
CISMeF synonym : 1b receptor, serotonin; 1dbeta receptor, serotonin; 1dbeta receptors, serotonin;
Is substance : O;
Origin ID : D044302;
UMLS CUI : C0535025;
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A serotonin receptor subtype found at high levels in the BASAL GANGLIA and the frontal
cortex. It plays a role as a terminal autoreceptor that regulates the rate of SEROTONIN
release from nerve endings. This serotonin receptor subtype is closely related to
and has similar drug binding properties as the 5-HT1D RECEPTOR. It is particularly
sensitive to the agonist SUMATRIPTAN and may be involved in mediating the drug's antimigraine
effect.