11-beta-hydroxysteroid dehydrogenase type 1

Preferred Label : 11-beta-hydroxysteroid dehydrogenase type 1;

MeSH definition : A low-affinity 11 beta-hydroxysteroid dehydrogenase found in a variety of tissues, most notably in LIVER; LUNG; ADIPOSE TISSUE; vascular tissue; OVARY; and the CENTRAL NERVOUS SYSTEM. The enzyme acts reversibly and can use either NAD or NADP as cofactors.;

MeSH synonym : 11beta hsd1 reductase; 11beta hydroxysteroid dehydrogenase type 1; 11beta-hsd1 reductase; 11beta-hsd1; 11beta-hydroxysteroid dehydrogenase type 1; 11 beta-Hydroxysteroid dehydrogenase type 1;

Registry Number MeSH : EC 1.1.1.146;

Is substance : O;

UNII : EC 1.1.1.146;

Details

Origin ID

D043205;

UMLS CUI

C0909868;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Indexing information
- 2-(1-(2-fluorophenyl)ethylamino)-5-methyl-5-(trifluoromethyl)thiazol-4(5H)-one [MeSH Supplementary Concept]
- 2-(1-(5-(cyclohexylcarbamoyl)-6-propylsulfanylpyridin-2-yl)-3-piperidyl)acetic acid [MeSH Supplementary Concept]
- 2-(3-noradamantylamino)-1-thia-3-azaspiro(4.4)non-2-en-4-one [MeSH Supplementary Concept]
- 3-(1-adamantyl)-6,7,8,9-tetrahydro-5H-(1,2,4)triazolo(4,3-a)azepine [MeSH Supplementary Concept]
- 4-(2-(1,1-dioxido-6-(2,4,6-trichlorophenyl)-1,2,6-thiadiazinan-2-yl)acetamido)adamantane-1-carboxamide [MeSH Supplementary Concept]
- 4-(2-adamantan-1-yl-2-oxoethoxymethyl)-N,N-dimethylbenzamide [MeSH Supplementary Concept]
- 4-(4-(2-adamantylcarbamoyl)-5-tert-butyl-pyrazol-1-yl)benzoic acid [MeSH Supplementary Concept]
- INCB 13739 [MeSH Supplementary Concept]
- N-(5-(aminocarbonyl)tricyclo(3.3.1.13,7)dec-2-yl)-alpha,alpha-dimethyl-4-(5-(trifluoromethyl)-2-pyridinyl)-1-piperazineacetamide [MeSH Supplementary Concept]
- N-(5-hydroxy-2-adamantyl)-2(4-(5-(trifluoromethyl)pyridin-2-yl)piperazin-1-yl)propionamide [MeSH Supplementary Concept]
- N-(5-hydroxy-2-adamantyl)-2-(4-(5-(trifluoromethyl)pyridin-2-yl)piperazin-1-yl)acetamide [MeSH Supplementary Concept]
- cochinchinoid K [MeSH Supplementary Concept]
- compound A (octyltriazole) [MeSH Supplementary Concept]
Record concept(s)
- 11-beta-Hydroxysteroid dehydrogenase type 1 [MeSH concept]
Related MeSH Supplementary Concept(s)
- HSD11B1 protein, human [MeSH Supplementary Concept]
- Hsd11b1 protein, mouse [MeSH Supplementary Concept]
See also inter- (CISMeF)
- Hyperandrogenism due to cortisone reductase deficiency [ICD-11 More detail]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]

Keyword's position in hierarchy(ies) :

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