MeSH definition : Transmembrane receptor for CLASS 3 SEMAPHORINS and several vascular endothelial growth
factor isoforms. Neuropilin-2 functions either as a homodimer or as a heterodimer
with NEUROPILIN-1. The binding affinity of neuropilin-2 varies for different class
3 semaphorin isoforms and is dependent on the composition of the dimer. The protein
also forms receptor complexes with plexins and with VEGF RECEPTORS, which alters the
binding characteristics of the receptor.;
Transmembrane receptor for CLASS 3 SEMAPHORINS and several vascular endothelial growth
factor isoforms. Neuropilin-2 functions either as a homodimer or as a heterodimer
with NEUROPILIN-1. The binding affinity of neuropilin-2 varies for different class
3 semaphorin isoforms and is dependent on the composition of the dimer. The protein
also forms receptor complexes with plexins and with VEGF RECEPTORS, which alters the
binding characteristics of the receptor.