integrin alpha3beta1

Preferred Label : integrin alpha3beta1;

MeSH definition : Cell surface receptor for LAMININ, epiligrin, FIBRONECTINS, entactin, and COLLAGEN. Integrin alpha3beta1 is the major integrin present in EPITHELIAL CELLS, where it plays a role in the assembly of BASEMENT MEMBRANE as well as in cell migration, and may regulate the functions of other integrins. Two alternatively spliced isoforms of the alpha subunit (INTEGRIN ALPHA3), are differentially expressed in different cell types.;

MeSH synonym : alpha3beta1 epiligrin receptor; alpha3beta1, integrin; cd49c-cd29; epiligrin receptor; epiligrin receptor, alpha3beta1; gap b3; integrin alpha(3)beta(1); receptor, alpha3beta1 epiligrin; receptor, epiligrin; vla-3; galactoprotein b3; laminin-5 receptor (alpha3beta1 integrin); alpha3beta1 integrin; integrin, alpha3beta1;

Is substance : O;

Details

Origin ID

D039201;

UMLS CUI

C0246766;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- physiology [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
Record concept(s)
- integrin alpha3beta1 [MeSH concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Receptor [UMLS semantic type]

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