integrin alpha6beta4

Preferred Label : integrin alpha6beta4;

MeSH definition : This intrgrin is a key component of HEMIDESMOSOMES and is required for their formation and maintenance in epithelial cells. Integrin alpha6beta4 is also found on thymocytes, fibroblasts, and Schwann cells, where it functions as a laminin receptor (RECEPTORS, LAMININ) and is involved in wound healing, cell migration, and tumor invasiveness.;

MeSH synonym : alpha(6)beta(4) epithelial integrin; antigen, a9; beta4 integrin, alpha6; laminin-5 receptor (alpha6beta4 integrin); tumor specific protein 180 complex; alpha6beta4, integrin; alpha(6)beta(4) integrin; tumor specific protein-180 complex; integrin alpha(6),beta(4); tsp-180; a9 antigen; alpha6 beta4 integrin; integrin, alpha6 beta4;

Is substance : O;

Details

Origin ID

D039161;

UMLS CUI

C0245301;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- physiology [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
Record concept(s)
- integrin alpha6beta4 [MeSH concept]
See also
- integrin alpha6 [MeSH Descriptor]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
- Receptor [UMLS semantic type]

Keyword's position in hierarchy(ies) :

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