MeSH definition : Nitro-phenanthrenes occurring in ARISTOLOCHIACEAE and other plants. They derive from
stephanine (APORPHINES) by oxidative ring cleavage. The nitro group is a reactive
alkylator (ALKYLATING AGENTS) that binds to biological macromolecules. Ingestion by
humans is associated with nephropathy (NEPHRITIS). There is no relationship to the
similar named aristolochene (SESQUITERPENES).;
Wikipedia link : https://en.wikipedia.org/wiki/Aristolochic acids;
Nitro-phenanthrenes occurring in ARISTOLOCHIACEAE and other plants. They derive from
stephanine (APORPHINES) by oxidative ring cleavage. The nitro group is a reactive
alkylator (ALKYLATING AGENTS) that binds to biological macromolecules. Ingestion by
humans is associated with nephropathy (NEPHRITIS). There is no relationship to the
similar named aristolochene (SESQUITERPENES).