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Preferred Label : hmg-box domains;

MeSH definition : DNA-binding domains present in proteins of the HMG-box superfamily including the archetypal HMGB PROTEINS, a number of sequence specific TRANSCRIPTION FACTORS, and other DNA-BINDING PROTEINS. The domains consist of 70-80 amino acids that form an L-shaped fold from three alpha-helical segments. The domain has the capacity to recognize and/or induce specific DNA structures and effect the accessibility of the DNA to other proteins involved in transcription, recombination, or DNA repair. (Note that not all HIGH MOBILITY GROUP PROTEINS contain this domain.);

MeSH synonym : hmg 1 box domain; domains, hmg-box; domains, hmg-1-box; domain, hmg-box; hmg-1-box domain; domain, hmg-1-box; hmg-1-box domains; hmg-box domain; HMG box domain; high mobility group-box domains; high mobility group box domains; HMG box domains;

MeSH annotation : HIGH MOBILITY GROUP PROTEINS is also available;

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Keyword's position in hierarchy(ies) : arborescence

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DNA-binding domains present in proteins of the HMG-box superfamily including the archetypal HMGB PROTEINS, a number of sequence specific TRANSCRIPTION FACTORS, and other DNA-BINDING PROTEINS. The domains consist of 70-80 amino acids that form an L-shaped fold from three alpha-helical segments. The domain has the capacity to recognize and/or induce specific DNA structures and effect the accessibility of the DNA to other proteins involved in transcription, recombination, or DNA repair. (Note that not all HIGH MOBILITY GROUP PROTEINS contain this domain.)

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03/05/2025


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