MeSH definition : An anchoring junction of the cell to a non-cellular substrate, similar in morphology
to halves of DESMOSOMES. They are composed of specialized areas of the plasma membrane
where INTERMEDIATE FILAMENTS bind on the cytoplasmic face to the transmembrane linkers,
INTEGRINS, via intracellular attachment proteins, while the extracellular domain of
the integrins binds to EXTRACELLULAR MATRIX PROTEINS.;
MeSH synonym : hemidesmosome;
Wikipedia link : https://en.wikipedia.org/wiki/Hemidesmosome;
An anchoring junction of the cell to a non-cellular substrate, similar in morphology
to halves of DESMOSOMES. They are composed of specialized areas of the plasma membrane
where INTERMEDIATE FILAMENTS bind on the cytoplasmic face to the transmembrane linkers,
INTEGRINS, via intracellular attachment proteins, while the extracellular domain of
the integrins binds to EXTRACELLULAR MATRIX PROTEINS.